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Find hotels in Upstate South Carolina, SC from $62
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Go beyond your typical stay in Upstate South Carolina
Check prices for these dates
Our top choices for Upstate South Carolina hotels

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (736 reviews)
$88 nightly
The price is $96
Jul 5 - Jul 6
Total with taxes and fees

The Point At Lake Hartwell
The Point At Lake HartwellTownville
$114 nightly
The price is $127
Jul 8 - Jul 9
Total with taxes and fees

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
7.8 out of 10, Good, (14 reviews)
$61 nightly
The price is $67
Jul 1 - Jul 2
Total with taxes and fees

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,003 reviews)
$139 nightly
The price is $154
Jul 1 - Jul 2
Total with taxes and fees

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (630 reviews)
$110 nightly
The price is $122
Jul 5 - Jul 6
Total with taxes and fees

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,005 reviews)
$123 nightly
The price is $135
Jul 2 - Jul 3
Total with taxes and fees

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (751 reviews)
$111 nightly
The price is $123
Jul 26 - Jul 27
Total with taxes and fees

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (617 reviews)
$148 nightly
The price is $164
Jul 1 - Jul 2
Total with taxes and fees

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,004 reviews)
$95 nightly
The price is $106
Jul 1 - Jul 2
Total with taxes and fees

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
$236 nightly
The price is $261
Jul 2 - Jul 3
Total with taxes and fees

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (869 reviews)
$149 nightly
The price is $165
Jul 5 - Jul 6
Total with taxes and fees

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (752 reviews)
$110 nightly
The price is $123
Jul 12 - Jul 13
Total with taxes and fees

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (471 reviews)
$139 nightly
The price is $152
Jul 2 - Jul 3
Total with taxes and fees

The Bleckley Inn
The Bleckley InnAnderson
9.8 out of 10, Exceptional, (420 reviews)
$176 nightly
The price is $195
Jul 5 - Jul 6
Total with taxes and fees

Deluxe Inn
Deluxe InnMauldin
8.4 out of 10, Very Good, (6 reviews)
$56 nightly
The price is $62
Jul 7 - Jul 8
Total with taxes and fees

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (858 reviews)
$104 nightly
The price is $114
Jul 12 - Jul 13
Total with taxes and fees

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.4 out of 10, Very Good, (944 reviews)
$85 nightly
The price is $94
Jul 5 - Jul 6
Total with taxes and fees

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (556 reviews)
$74 nightly
The price is $83
Jul 1 - Jul 2
Total with taxes and fees

Inn @ Clemson
Inn @ ClemsonClemson
8.0 out of 10, Very Good, (1,005 reviews)
$87 nightly
The price is $97
Jul 7 - Jul 8
Total with taxes and fees

The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown ClemsonClemson
9.8 out of 10, Exceptional, (829 reviews)
$144 nightly
The price is $160
Jul 1 - Jul 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (85 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Fairview Corners I and Discovery Island Water Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Comfort Inn Greenville - Haywood Mall
10/10 Excellent
More cheap stays in Upstate South Carolina

Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
$63 nightly
The price is $69 total per night from Jul 20 to Jul 21
$69 total
Jul 20 - Jul 21
Total with taxes and fees
5.6/10 (1,012 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
29 properties
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